When breast cancer spreads to the brain

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Secondary breast cancer is breast cancer that has spread from the breast to other parts of the body. Breast cancer starts as a lump in the breast - this is primary breast cancer. In many women, primary breast cancer does not come back after treatment.

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I wonder if anyone can share their experiences. My mum has recently been diagnosed with multiple brain mets - she had breast cancer in for which she had a radical bilateral mastectomies and chemo and radiotherapy - she then had a recurrence in March 17 and we found out it had spread to her adrenal gland and nodes in her chest - she had just finished chemo and is having 3 weekly herceptin injections when she was rushed to hospital and we found out that it had spread to her brain. If anyone has experienced anything similar and would be prepared to share that experience I would so grateful as I feel so hopeless xx.

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Sometimes, brain metastases are found when breast cancer is first diagnosed, but the majority of the time, brain metastases occur as a distant recurrence of an early-stage breast cancer that was treated in the past. What symptoms may occur, and what treatment options are available if your breast cancer spreads to your brain? Overall, brain metastases occur in 15 to 24 percent of women with metastatic breast cancer.

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Skip to Content. Use the menu to see other pages. This section explains the types of treatments that are the standard of care for metastatic breast cancer.

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Because of improvements in the treatment of patients with metastatic breast cancer, the development of brain metastases BM has become a major limitation of life expectancy and quality of life for many breast cancer patients. The improvement of management strategies for BM is thus an important clinical challenge, especially among high-risk patients such as human epidermal growth factor receptor 2-positive and triple-negative patients. However, the formation of BM as a multistep process is thus far poorly understood.

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For most, the breast cancer has already traveled to another part of the body, such as the bones, liver, or lung. The risk of cancer spread to the brain is usually highest for women with more aggressive subtypes of breast cancer, such as HER2-positive or triple-negative breast cancer. If your doctor suspects brain metastasis, he or she will order an MRI magnetic resonance imaging study of the brain, often with contrast solution.

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What is secondary breast cancer in the brain? Newly diagnosed or worried about a symptom? What is leptomeningeal metastases?

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Brain metastasis is cancer that started in another part of the body and spread to the brain. Brain metastasis is not the same as cancer that starts in the brain called primary brain cancer. Brain metastases are much more common than primary brain cancer.

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Most cancers kill because tumor cells spread beyond the primary site to invade other organs. Now, a USC study of brain-invading breast cancer cells circulating in the blood reveals they have a molecular signature indicating specific organ preferences. The findings, which appear in Cancer Discoveryhelp explain how tumor cells in the blood target a particular organ and may enable the development of treatments to prevent the spread of cancers, known as metastasis.

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This shows tumors that developed after cancer from a tumor elsewhere in the body spread metastasized to the brain. Brain metastases occur when cancer cells spread from their original site to the brain. Any cancer can spread to the brain, but the types most likely to cause brain metastases are lung, breast, colon, kidney and melanoma.


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